Here is the to get a clean, blank ePSXe 001.mcr :
MD5: d41d8cd98f00b204e9800998ecf8427e
The culprit is almost always a missing or corrupted file. Epsxe 001.mcr Download
Never trust a downloaded memory card from an unknown source. Create your own blank one using the steps above, or download the verified blank file linked in this post. Here is the to get a clean, blank ePSXe 001