Bioprocess Engineering Basic Concepts 2nd Edition Solution -

4.1. A stirred-tank bioreactor has a volume of 2000 L and operates at a stirrer speed of 100 rpm. If the power input is 2 kW, what is the power per unit volume?

Solution: Mass of medium = 1000 L * 1000 g/L = 1,000,000 g or 1000 kg. Energy required = 1000 kg * 4.2 kJ/kg°C * (37°C - 20°C) = 1000 * 4.2 * 17 = 71,400 kJ. Bioprocess Engineering Basic Concepts 2nd Edition Solution

2.1. A bioreactor contains 1000 L of medium with an initial cell concentration of 1 g/L. If 500 L of medium is added, what is the new cell concentration? Solution: Mass of medium = 1000 L *

3.1. A bioprocess requires heating 1000 L of medium from 20°C to 37°C. If the specific heat capacity of the medium is 4.2 kJ/kg°C and the density is 1 g/mL, what is the energy required? A bioreactor contains 1000 L of medium with

1.2. Describe the differences between batch, fed-batch, and continuous bioprocesses.